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De novo design of alpha-amylase inhibitor: A small linear mimetic of macromolecular proteinaceous ligands

SYSNO ASEP	0025435
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Ostatní články
Title	De novo design of alpha-amylase inhibitor: A small linear mimetic of macromolecular proteinaceous ligands
Title	De novo design inhibitoru alfa-amylas: Malé linearní mimetikum makromolekulárních proteinových ligandů
Author(s)	Marešová, Lucie (UOCHB-X)_RID Pavlík, Manfred (UOCHB-X) Horn, Martin (UOCHB-X)_{RID, ORCID} Mareš, Michael (UOCHB-X)_{RID, ORCID}
Source Title	Chemistry & Biology. - : Elsevier - ISSN 1074-5521 Roč. 12, č. 12 (2005), 1349-1357
Number of pages	9 s.
Language	eng - English
Country	US - United States
Keywords	amylase ; peptide inhibitor ; combinatorial chemistry
Subject RIV	CE - Biochemistry
R&D Projects	GP203/02/P081 GA ČR - Czech Science Foundation (CSF)
	OC D16.001 GA MŠMT - Ministry of Education, Youth and Sports (MEYS)
CEZ	AV0Z40550506 - UOCHB-X (2005-2011)
Annotation	First low molecular weight inhibitor of alpha-amylases based on acyclic peptidic scaffold was designed de novo through the use of combinatorial chemistry.
Workplace	Institute of Organic Chemistry and Biochemistry
Contact	asep@uochb.cas.cz ; Kateřina Šperková, Tel.: 232 002 584 ; Viktorie Chládková, Tel.: 232 002 434
Year of Publishing	2006

Number of the records: 1