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Longitudinal measurements of total body water and body composition in healthy volunteers by online breath deuterium measurement and other near-subject methods

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    SYSNO ASEP0021163
    Document TypeJ - Journal Article
    R&D Document TypeJournal Article
    Subsidiary JOstatní články
    TitleLongitudinal measurements of total body water and body composition in healthy volunteers by online breath deuterium measurement and other near-subject methods
    TitlePrůběžná měření celkové vody v těle a tělesné skladby u zdravých dobrovolníků pomocí přímého měření deuteria v dechu a dalších metod
    Author(s) Engel, B. (GB)
    Španěl, Patrik (UFCH-W) RID, ORCID
    Smith, D. (GB)
    Diskin, A. M. (GB)
    Davis, S. J. (GB)
    Source TitleInternational Journal of Body Composition Research - ISSN 1479-456X
    Roč. 2, č. 3 (2005), s. 99-106
    Number of pages8 s.
    Languageeng - English
    CountryGB - United Kingdom
    Keywordstotal body water ; deuterium isotope dilution ; FA-MS ; bio-impendance
    Subject RIVCF - Physical ; Theoretical Chemistry
    R&D ProjectsGA203/00/0632 GA ČR - Czech Science Foundation (CSF)
    CEZAV0Z40400503 - UFCH-W (2005-2011)
    AnnotationRapid quantification of breath deuterium abundance by flowing afterglow mass spectrometry (FA-MS) enables accurate measurement of total body water (TBW), which combined with other techniques such as bioelectrical impedance analysis (BIA) and anthropometrics enables near-subject assessment of body composition. This study assessed the comparative reproducibility and inter-relationship of these methods in healthy subjects over 12 months. Detailed bedside composition was performed in 22 subjects, (10 male) aged 28–79 with body mass index (BMI) ranging from 21–38 at baseline and again at one year. Techniques included FA-MS deuterium dilution, BIA, skin-fold thickness (SFT) and soft tissue ultrasound measurement of fat and muscle depth. Short-term reproducibility for each method was established. Within and between technique comparisons of measurement were made from Pearson’s linear regression, coefficient of variation (CV) and Bland-Altman analysis.
    WorkplaceJ. Heyrovsky Institute of Physical Chemistry
    ContactMichaela Knapová, michaela.knapova@jh-inst.cas.cz, Tel.: 266 053 196
    Year of Publishing2006
Number of the records: 1  

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