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Selective HDAC6 inhibitors improve anti-PD-1 immune checkpoint blockade therapy by decreasing the anti-inflammatory phenotype of macrophages and down-regulation of immunosuppressive proteins in tumor cells

  1. 1.
    Knox, T. - Sahakian, E. - Banik, D. - Hadley, M. - Palmer, E. - Noonepalle, S. - Kim, J. - Powers, J. - Gracia-Hernandez, M. - Oliveira, V. - Cheng, F. - Chen, J. - Bařinka, Cyril - Pinilla-Ibarz, J. - Lee, N. H. - Kozikowski, A. - Villagra, A.
    Selective HDAC6 inhibitors improve anti-PD-1 immune checkpoint blockade therapy by decreasing the anti-inflammatory phenotype of macrophages and down-regulation of immunosuppressive proteins in tumor cells.
    Scientific Reports. Roč. 9, APR 16 2019 (2019), č. článku 6136. ISSN 2045-2322. E-ISSN 2045-2322
    OECD category: Biochemistry and molecular biology
    Impact factor: 3.998, year: 2019
    Method of publishing: Open access
    https://www.nature.com/articles/s41598-019-42237-3
    http://hdl.handle.net/11104/0301209
Number of the records: 1  

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