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Discovery of the first dual inhibitor of the 5-lipoxygenase-activating protein and soluble epoxide hydrolase using pharmacophore-based virtual screening
- 1.0474823 - ÚEB 2018 RIV GB eng J - Journal Article
Temml, V. - Garscha, U. - Romp, E. - Schubert, G. - Gerstmeier, J. - Kutil, Zsófia - Matuszczak, B. - Waltenberger, B. - Stuppner, H. - Werz, O. - Schuster, D.
Discovery of the first dual inhibitor of the 5-lipoxygenase-activating protein and soluble epoxide hydrolase using pharmacophore-based virtual screening.
Scientific Reports. Roč. 7, FEB 20 (2017), č. článku 42751. ISSN 2045-2322. E-ISSN 2045-2322
Institutional support: RVO:61389030
Keywords : activating protein * drug discovery * leukotriene biosynthesis * inflammatory diseases * conformer generation * arachidonic-acid * flap * challenges * asthma * risk
OECD category: Physiology (including cytology)
Impact factor: 4.122, year: 2017
Permanent Link: http://hdl.handle.net/11104/0271773File Download Size Commentary Version Access 2017_Temml_SCIENTIFIC REPORTS_42751.pdf 2 759.2 KB Other open-access
Number of the records: 1