Synthesis, biological evaluation and molecular modeling of a novel series of 7-azaindole based tri-heterocyclic compounds as potent CDK2/Cyclin E inhibitors

0459008 - ÚEB 2017 RIV FR eng J - Journal Article
Baltus, C.B. - Jorda, Radek - Marot, Ch. - Berka, K. - Bazgier, Václav - Kryštof, Vladimír - Prie, G. - Viaud-Massuard, M.C.
Synthesis, biological evaluation and molecular modeling of a novel series of 7-azaindole based tri-heterocyclic compounds as potent CDK2/Cyclin E inhibitors.
European Journal of Medicinal Chemistry. Roč. 108, JAN 27 (2016), s. 701-719. ISSN 0223-5234. E-ISSN 1768-3254
R&D Projects: GA MŠMT(CZ) LO1204
Institutional support: RVO:61389030
Keywords : Cyclin-dependent kinase 2 * Kinase inhibitors * Anti-tumor agent
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 4.519, year: 2016

Permanent Link: http://hdl.handle.net/11104/0259205