Number of the records: 1
Pregnane-based steroids are novel positive NMDA receptor modulators that may compensate for the effect of loss-of-function disease-associated GRIN mutations
- 1.0558978 - FGÚ 2023 RIV GB eng J - Journal Article
Kysilov, Bohdan - Hrčka Krausová, Barbora - Vyklický, Vojtěch - Smejkalová, Tereza - Kořínek, Miloslav - Horák, Martin - Chodounská, Hana - Kudová, Eva - Černý, Jiří - Vyklický ml., Ladislav
Pregnane-based steroids are novel positive NMDA receptor modulators that may compensate for the effect of loss-of-function disease-associated GRIN mutations.
British Journal of Pharmacology. Roč. 179, č. 15 (2022), s. 3970-3990. ISSN 0007-1188. E-ISSN 1476-5381
R&D Projects: GA ČR(CZ) GA20-17945S; GA MZd(CZ) EF16_025/0007444; GA TA ČR(CZ) TN01000013
Institutional support: RVO:67985823 ; RVO:61388963
Keywords : GRIN channelopathy * NMDA receptor * positive allosteric modulator * steroids * transmembrane domain
OECD category: Neurosciences (including psychophysiology
Impact factor: 7.3, year: 2022
Method of publishing: Open access
https://doi.org/10.1111/bph.15841
Permanent Link: https://hdl.handle.net/11104/0332640
Number of the records: 1