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Synthesis and Biological Evaluation of Phosphoester and Phosphorothioate Prodrugs of STING Agonist 3′,3′-c-Di(2′F,2′dAMP)

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    0543611 - ÚOCHB 2022 RIV US eng J - Journal Article
    Pimková Polidarová, Markéta - Břehová, Petra - Kaiser, Martin Maxmilian - Smola, Miroslav - Dračínský, Martin - Smith, Joshua - Marek, Aleš - Dejmek, Milan - Šála, Michal - Gutten, Ondrej - Rulíšek, Lubomír - Novotná, Barbora - Brázdová, Andrea - Janeba, Zlatko - Nencka, Radim - Bouřa, Evžen - Páv, Ondřej - Birkuš, Gabriel
    Synthesis and Biological Evaluation of Phosphoester and Phosphorothioate Prodrugs of STING Agonist 3′,3′-c-Di(2′F,2′dAMP).
    Journal of Medicinal Chemistry. Roč. 64, č. 11 (2021), s. 7596-7616. ISSN 0022-2623. E-ISSN 1520-4804
    R&D Projects: GA MŠMT(CZ) EF16_019/0000729; GA ČR(CZ) GA20-08772S
    Institutional support: RVO:61388963
    Keywords : DNA sensor * interferon genes * cyclic GMP-AMP
    OECD category: Medicinal chemistry
    Impact factor: 8.039, year: 2021
    Method of publishing: Limited access
    https://doi.org/10.1021/acs.jmedchem.1c00301

    Permanent Link: http://hdl.handle.net/11104/0320799
     
Number of the records: 1  

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