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Thermodynamic and structural analysis of HIV protease resistance to darunavir - analysis of heavily mutated patient- derived HIV-1 proteases

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    0427922 - ÚOCHB 2015 RIV GB eng J - Journal Article
    Kožíšek, Milan - Lepšík, Martin - Grantz Šašková, Klára - Brynda, Jiří - Konvalinka, Jan - Řezáčová, Pavlína
    Thermodynamic and structural analysis of HIV protease resistance to darunavir - analysis of heavily mutated patient- derived HIV-1 proteases.
    FEBS Journal. Roč. 281, č. 7 (2014), s. 1834-1847. ISSN 1742-464X. E-ISSN 1742-4658
    R&D Projects: GA ČR GAP207/11/1798
    Grant - others:OPPC(XE) CZ.2.16/3.1.00/24016
    Institutional support: RVO:61388963 ; RVO:68378050
    Keywords : enthropic contribution * HIV protease inhibitors * isothermal titration calorimetry * resistance mutation * X-ray crystallography
    Subject RIV: CE - Biochemistry
    Impact factor: 4.001, year: 2014

    Permanent Link: http://hdl.handle.net/11104/0233503
     
Number of the records: 1  

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