Photochemical Functionalization of Helicenes.

0511585 - ÚCHP 2021 RIV DE eng J - Journal Article
Jakubec, Martin - Ghosh, I. - Storch, Jan - König, B.
Photochemical Functionalization of Helicenes.
Chemistry - A European Journal. Roč. 26, č. 2 (2020), s. 543-547. ISSN 0947-6539. E-ISSN 1521-3765
R&D Projects: GA MŠMT(CZ) EF16_027/0007931; GA MPO FV10082
Institutional support: RVO:67985858
Keywords : helicene functionalizations * visible light * photoredox
OECD category: Organic chemistry
Impact factor: 5.236, year: 2020
Method of publishing: Open access
https://chemistry-europe.onlinelibrary.wiley.com/doi/epdf/10.1002/chem.201904169

We describe here a visible light photochemical approach for practical helicene functionalization at very mild reaction conditions. The photochemical reactions allow the regiospecific and innate late-stage functionalization of helicenes and are easily executed either via the activation of C(sp2)–Br bonds in helicenes using K2CO3 as inorganic base or direct C(sp2)–H helicene bond functionalization under oxidative photoredox reaction conditions. Overall, using these transformations six different functional groups are introduced to the helicene scaffold via C–C and four different C–heteroatom bond-forming reactions.
Permanent Link: http://hdl.handle.net/11104/0305538