Number of the records: 1
Modulation of gap-junctional intercellular communication by a series of cyanobacterial samples from nature and laboratory cultures
- 1.0369524 - BÚ 2012 RIV GB eng J - Journal Article
Nováková, K. - Babica, Pavel - Adamovský, O. - Bláha, Luděk
Modulation of gap-junctional intercellular communication by a series of cyanobacterial samples from nature and laboratory cultures.
Toxicon. Roč. 58, č. 1 (2011), s. 76-84. ISSN 0041-0101. E-ISSN 1879-3150
R&D Projects: GA ČR GA524/08/0496
Institutional research plan: CEZ:AV0Z60050516
Keywords : cyanotoxins * gap-junctional intercellular communication * tumor promotion
Subject RIV: EF - Botanics
Impact factor: 2.508, year: 2011
Extracts and exudates of cyanobacteria inhibit gap-junctional intercellular communication in rat liver cells in vitro. Inhibitory effects on GJIC were caused by chemicals different from microcystin and cylindrospermopsin, which indicates an existence of novel tumor promoting cyanotoxins. The effects were induced by common bloom-forming cyanobacteria (Anabaena, Aphanizomenon, Microcystis, Planktothrix), but the inhibitory potencies of extrats and exudates were species- and strain-specific.
Permanent Link: http://hdl.handle.net/11104/0203567
Number of the records: 1