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Synthesis of ester prodrugs of 9-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]-2,6-diaminopurine (HPMPDAP) as anti-poxvirus agents

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    0350272 - ÚOCHB 2011 RIV US eng J - Journal Article
    Krečmerová, Marcela - Holý, Antonín - Andrei, G. - Pomeisl, Karel - Tichý, Tomáš - Břehová, Petra - Masojídková, Milena - Dračínský, Martin - Pohl, Radek - Laflamme, G. - Naesens, L. - Hui, H. - Cihlař, T. - Neyts, J. - De Clercq, E. - Balzarini, J. - Snoeck, R.
    Synthesis of ester prodrugs of 9-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]-2,6-diaminopurine (HPMPDAP) as anti-poxvirus agents.
    Journal of Medicinal Chemistry. Roč. 53, č. 19 (2010), s. 6825-6837. ISSN 0022-2623. E-ISSN 1520-4804
    R&D Projects: GA MŠMT 1M0508; GA MŠMT(CZ) ME10040
    Grant - others:NIH(US) 1UC1 AI062540-01
    Institutional research plan: CEZ:AV0Z40550506
    Keywords : phosphonates * prodrugs * poxvirus * herpes virus * bioterrorism
    Subject RIV: CC - Organic Chemistry
    Impact factor: 5.207, year: 2010
    Permanent Link: http://hdl.handle.net/11104/0190312
     
     
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