Converting Insulin-like Growth Factors 1 and 2 into High-Affinity Ligands for Insulin Receptor Isoform A by the Introduction of an Evolutionarily Divergent Mutation

Macháčková, K., Chrudinová, M., Radosavljević, J., Potalitsyn, P., Křížková, K., Fábry, M., Selicharová, I., Collinsová, M., Brzozowski, A. M., Žáková, L., Jiráček, J. Converting Insulin-like Growth Factors 1 and 2 into High-Affinity Ligands for Insulin Receptor Isoform A by the Introduction of an Evolutionarily Divergent Mutation. Biochemistry. 2018, 57(16), 2373-2382. ISSN 0006-2960. Available: doi: 10.1021/acs.biochem.7b01260.