Pyrazolo[4,3-d]pyrimidine Bioisostere of Roscovitine: Evaluation of a Novel Selective Inhibitor of Cyclin-Dependent Kinases with Antiproliferative Activity

Jorda, R., Havlíček, L., McNae, I. W., Walkinshaw, M. D., Voller, J., Šturc, A., Navrátilová, J., Kuzma, M., Mistrik, M., Bártek, J., Strnad, M., Kryštof, V. Pyrazolo[4,3-d]pyrimidine Bioisostere of Roscovitine: Evaluation of a Novel Selective Inhibitor of Cyclin-Dependent Kinases with Antiproliferative Activity. Journal of Medicinal Chemistry. 2011, 54(8), 2980-2993. ISSN 0022-2623. E-ISSN 1520-4804. Available: doi: 10.1021/jm200064p