Pregnane-based steroids are novel positive NMDA receptor modulators that may compensate for the effect of loss-of-function disease-associated GRIN mutations

KYSILOV, Bohdan, HRČKA KRAUSOVÁ, Barbora, VYKLICKÝ, Vojtěch, SMEJKALOVÁ, Tereza, KOŘÍNEK, Miloslav, HORÁK, Martin, CHODOUNSKÁ, Hana, KUDOVÁ, Eva, ČERNÝ, Jiří, VYKLICKÝ ML., Ladislav. Pregnane-based steroids are novel positive NMDA receptor modulators that may compensate for the effect of loss-of-function disease-associated GRIN mutations. British Journal of Pharmacology. 2022, 179(15), 3970-3990. ISSN 0007-1188. E-ISSN 1476-5381. Available: doi: 10.1111/bph.15841.