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Synthesis and Biological Evaluation of Phosphoester and Phosphorothioate Prodrugs of STING Agonist 3′,3′-c-Di(2′F,2′dAMP)

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    PIMKOVÁ POLIDAROVÁ, Markéta, BŘEHOVÁ, Petra, KAISER, Martin Maxmilian, SMOLA, Miroslav, DRAČÍNSKÝ, Martin, SMITH, Joshua, MAREK, Aleš, DEJMEK, Milan, ŠÁLA, Michal, GUTTEN, Ondrej, RULÍŠEK, Lubomír, NOVOTNÁ, Barbora, BRÁZDOVÁ, Andrea, JANEBA, Zlatko, NENCKA, Radim, BOUŘA, Evžen, PÁV, Ondřej, BIRKUŠ, Gabriel. Synthesis and Biological Evaluation of Phosphoester and Phosphorothioate Prodrugs of STING Agonist 3′,3′-c-Di(2′F,2′dAMP). Journal of Medicinal Chemistry. 2021, 64(11), 7596-7616. ISSN 0022-2623. E-ISSN 1520-4804. Available: doi: 10.1021/acs.jmedchem.1c00301.
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