The scope of detector Medipix2 in micro-radiography of biological samples

0368680 - BC 2012 RIV NL eng J - Journal Article
Dammer, J. - Weyda, František - Jakůbek, J. - Škrabal, P. - Sopko, V. - Vavřík, D.
The scope of detector Medipix2 in micro-radiography of biological samples.
Nuclear Instruments & Methods in Physics Research Section A. Roč. 633, č. 1 (2011), s. 175-176. ISSN 0168-9002. E-ISSN 1872-9576.
[International Workshop on Radiation Imaging Detectors /11./. Praha, 29.06.2009-03.07.2009]
R&D Projects: GA MŠMT 2B06005
Grant - others:Ministerstvo školství(CZ) 6840770040; GA MŠk(CZ) 1P04LA211; GA MŠk(CZ) LC06041
Program: 1P; LC
Institutional research plan: CEZ:AV0Z50070508
Keywords : x-ray imaging * digital radiography * photon and x-ray detectors
Subject RIV: EA - Cell Biology
Impact factor: 1.207, year: 2011

We present our experimental setup devoted to high resolution X-ray micro-radiography that is suitable for imaging of small biological samples. The photon source is a FeinFocus micro-focus X-ray tube. The single photon counting pixel device Medipix2 serves as imaging area. Recently used imaging detectors as radiography films or scintillator detectors, cannot visualize required information about inner structure of scanned sample. Detectors Medipix2 do not suffer from so-called dark current noise and work in unlimited dynamic range. These features of detectors confer high quality and high contrast of final images. The radiographic imaging with detectors Medipix2 represents non-invasive and non-destructive method of investigation. Hereby, we demonstrate results of micro-radiographic study of internal structures of tiny biological samples.
Permanent Link: http://hdl.handle.net/11104/0202961