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Regenerative Potential of PDL-Derived Small Extracellular Vesicles
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SYSNO ASEP 0637012 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Regenerative Potential of PDL-Derived Small Extracellular Vesicles Author(s) Birjandi, A. A. (GB)
Lynham, S. (GB)
Matalová, Eva (UZFG-Y) ORCID
Ghuman, M. (GB)
Sharpe, Paul (UZFG-Y)Source Title Journal of Periodontal Research - ISSN 0022-3484
Roč. 60, č. 4 (2025), s. 392-394Number of pages 3 s. Publication form Print - P Language eng - English Country DK - Denmark Keywords periodontal treatment ; stem cells OECD category Cell biology R&D Projects GA21-21409S GA ČR - Czech Science Foundation (CSF) Method of publishing Open access Institutional support UZFG-Y - RVO:67985904 UT WOS 001362737900001 EID SCOPUS 85210004537 DOI https://doi.org/10.1111/jre.13356 Annotation The optimal healing outcome following periodontal treatment is complete periodontal regeneration which is very rarely achieved. Periodontal ligament (PDL) cells promote direct connective tissue attachment consistent with regenerative outcomes, whereas gingival connective tissue is not innately permissive. An alternative approach to promote regeneration is to alter the potential of gingival connective tissue to promote bone formation and connective tissue attachment. Multipotent mesenchymal stem cells have been isolated from gingival tissues and promote peri-implant bone regeneration Workplace Institute of Animal Physiology and Genetics Contact Jana Zásmětová, knihovna@iapg.cas.cz, Tel.: 315 639 554 Year of Publishing 2026 Electronic address https://onlinelibrary.wiley.com/doi/10.1111/jre.13356
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