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The pangenome of hexaploid bread wheat
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SYSNO ASEP 0476570 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title The pangenome of hexaploid bread wheat Author(s) Montenegro, J. D. (AU)
Golicz, A. A. (AU)
Bayer, P.E. (AU)
Hurgobin, B. (AU)
Lee, H. T. (AU)
Chan, C. K. K. (AU)
Visendi, P. (AU)
Lai, K. (AU)
Doležel, Jaroslav (UEB-Q) RID, ORCID
Batley, J. (AU)
Edwards, D. (AU)Number of authors 11 Source Title Plant Journal. - : Wiley - ISSN 0960-7412
Roč. 90, č. 5 (2017), s. 1007-1013Number of pages 7 s. Language eng - English Country GB - United Kingdom Keywords database ; diversity ; genome ; pangenome ; single nucleotide polymorphisms ; Triticum aestivum ; wheat Subject RIV EB - Genetics ; Molecular Biology OECD category Plant sciences, botany R&D Projects LO1204 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) Institutional support UEB-Q - RVO:61389030 UT WOS 000403346500014 EID SCOPUS 85017376392 DOI 10.1111/tpj.13515 Annotation There is an increasing understanding that variation in gene presence–absence plays an important role in the heritability of agronomic traits, however, there have been relatively few studies on variation in gene presence–absence in crop species. Hexaploid wheat is one of the most important food crops in the world and intensive breeding has reduced the genetic diversity of elite cultivars. Major efforts have produced draft genome assemblies for the cultivar Chinese Spring, but it is unknown how well this represents the genome diversity found in current modern elite cultivars. In this study we build an improved reference for Chinese Spring and explore gene diversity across 18 wheat cultivars. We predict a pangenome size of 140 500 ± 102 genes, a core genome of 81 070 ± 1631 genes and an average of 128 656 genes in each cultivar. Functional annotation of the variable gene set suggests that it is enriched for genes that may be associated with important agronomic traits. In addition to variation in gene presence, more than 36 million intervarietal single nucleotide polymorphisms were identified across the pangenome. This study of the wheat pangenome provides insight into genome diversity in elite wheat as a basis for genomics-based improvement of this important crop. A wheat pangenome, GBrowse, is available at http://appliedbioinformatics.com.au/cgi-bin/gb2/gbrowse/WheatPan/, and data are available to download from http://wheatgenome.info/wheat_genome_databases.php. Workplace Institute of Experimental Botany Contact David Klier, knihovna@ueb.cas.cz, Tel.: 220 390 469 Year of Publishing 2018
Number of the records: 1