Genetic and phytochemical variability of six Teucrium arduini L. populations and their antioxidant/prooxidant behaviour examined by biochemical, macromolecule- and cell-based approaches

Šamec, D.; Durgo, K.; Grúz, Jiří; Kremer, D.; Kosalec, I.; Piljac-Žegarac, J.; Salopek-Sondi, N.

doi:https://dx.doi.org/10.1016/j.foodchem.2014.07.135

Number of the records: 1

Genetic and phytochemical variability of six Teucrium arduini L. populations and their antioxidant/prooxidant behaviour examined by biochemical, macromolecule- and cell-based approaches

1.

SYSNO ASEP	0447019
Document Type	J - Journal Article
R&D Document Type	Journal Article
Subsidiary J	Článek ve WOS
Title	Genetic and phytochemical variability of six Teucrium arduini L. populations and their antioxidant/prooxidant behaviour examined by biochemical, macromolecule- and cell-based approaches
Author(s)	Šamec, D. (HR) Durgo, K. (HR) Grúz, Jiří (UEB-Q)_{RID, ORCID} Kremer, D. (HR) Kosalec, I. (HR) Piljac-Žegarac, J. (HR) Salopek-Sondi, N. (HR)
Source Title	Food Chemistry. - : Elsevier - ISSN 0308-8146 Roč. 186, SI (2015), s. 298-305
Number of pages	8 s.
Language	eng - English
Country	NL - Netherlands
Keywords	Antioxidative/prooxidative activity ; Cytotoxicity ; Ethnopharmacology
Subject RIV	EF - Botanics
R&D Projects	LK21306 GA MŠMT - Ministry of Education, Youth and Sports (MEYS)
Institutional support	UEB-Q - RVO:61389030
UT WOS	000356128400044
DOI	10.1016/j.foodchem.2014.07.135
Annotation	Teucrium arduini L., an Ilyric-Balcanic endemic species, has been reported for decades as a valuable plant used in traditional medicine for treating digestive disorders. The present study evaluated genetic and phytochemical variability of six T. arduini populations in order to determine factors that influence an accumulation of polyphenolic compounds. Results strongly suggest that a phytochemical variation was caused by environmental rather than genetic factors. T. arduini leaf extract from the locality Ucka, which accumulated significantly more polyphenolic phytochemicals in comparison to others, showed antioxidant activity in DNA and lipid bioassays. Furthermore, the same extract exhibited prooxidant behaviour at protein level and induce formation of reactive oxygen species in human laryngeal carcinoma cells causing cytotoxic activity, in a dose dependent manner. All the results of the present study suggested that T. arduini extract could be responsible for antioxidative/prooxidative mechanisms and would help in determination of optimal conditions for their ethnopharmacological use.
Workplace	Institute of Experimental Botany
Contact	David Klier, knihovna@ueb.cas.cz, Tel.: 220 390 469
Year of Publishing	2016

Number of the records: 1