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Activating transcription factor 3 regulates immune and metabolic homeostasis

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    0380846 - BC 2013 RIV US eng J - Journal Article
    Ryneš, J. - Donohoe, C. D. - Frommolt, P. - Brodesser, S. - Jindra, Marek - Uhlířová, M.
    Activating transcription factor 3 regulates immune and metabolic homeostasis.
    Molecular and Cellular Biology. Roč. 32, č. 19 (2012), s. 3949-3962. ISSN 0270-7306
    R&D Projects: GA ČR(CZ) GD204/09/H058
    Institutional support: RVO:60077344
    Keywords : metabolic homeostasis
    Subject RIV: EB - Genetics ; Molecular Biology
    Impact factor: 5.372, year: 2012

    Using Drosophila genetics and systems biology, this study shows that the bZIP transcription factor Atf3 links metabolic and innate immune responses to safeguard homeostasis. The single fly Atf3 gene likely integrates functions of two paralogous mammalian genes.
    Permanent Link: http://hdl.handle.net/11104/0211454
     
Number of the records: 1