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Impact of heat-inactivated Lactobacillus casei and Lactobacillus paracasei strains on cytokine responses in whole blood cell cultures of children with atopic dermatitis

  1. 1. 0348114 - MBU-M 2011 RIV CZ eng J - Journal Article
    Cukrowska, B. - Rosiak, I. - Klewicka, E. - Motyl, I. - Schwarzer, Martin - Libudzisz, Z. - Kozáková, Hana
    Impact of heat-inactivated Lactobacillus casei and Lactobacillus paracasei strains on cytokine responses in whole blood cell cultures of children with atopic dermatitis.
    Folia Microbiologica. Roč. 55, č. 3 (2010), s. 277-280. ISSN 0015-5632
    R&D Projects: GA ČR GA303/09/0449
    Institutional research plan: CEZ:AV0Z50200510
    Keywords : lactobacillus casei * atopic dermatitis * allergy
    Subject RIV: EC - Immunology
    Impact factor: 0.977, year: 2010

    Heat-inactivated Lactobacillus casei LOCK 0900, L. casei LOCK 0908 and Lactobacillus paracasei LOCK 0919 strains, applied to blood cell cultures obtained from children with atopic dermatitis induced production of anti-allergic TH1 and regulatory cytokines but did not stimulate pro-allergic interleukin-5. The lactobacilli-mixture remarkably enhanced the TH1 response compared to single strains. The mixture of Lactobacillus strains represents a probiotic bacterial preparation modulating in vitro cytokine profile of allergic children towards anti-allergic TH1 response
    Permanent Link: http://hdl.handle.net/11104/0188726