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Patterning by heritage in mouse molar row development

  1. 1. 0347389 - UEM-P 2011 RIV US eng J - Journal Article
    Procházka, Jan - Pantalacci, S. - Churavá, Svatava - Rothová, Michaela - Lambert, A. - Lesot, H. - Klein, O. - Peterka, Miroslav - Laudet, V. - Peterková, Renata
    Patterning by heritage in mouse molar row development.
    Proceedings of the National Academy of Sciences of the United States of America. Roč. 107, č. 35 (2010), s. 15497-15502. ISSN 0027-8424
    R&D Projects: GA ČR(CZ) GA304/07/0223
    Institutional research plan: CEZ:AV0Z50390512
    Keywords : rudiment * signaling center * tooth evolution
    Subject RIV: EA - Cell Biology
    Impact factor: 9.771, year: 2010

    It is known from paleontology studies that two premolars have been lost during mouse evolution. During mouse mandible development, two bud-like structures transiently form that may represent rudimentary precursors of the lost premolars. This study highlights how rudiments of lost structures can stay integrated and participate in morphogenesis of functional organs and help in understanding their evolution, as Darwin suspected long ago.
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