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Improvement of the accuracy by the measurement of the electrical cell membrane parameters

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    0142309 - FGU-C 20020031 RIV CZ eng J - Journal Article
    Rohlíček, Vojtěch - Rech, František
    Improvement of the accuracy by the measurement of the electrical cell membrane parameters.
    Physiological Research. Roč. 51, č. 2 (2002), s. 169-177. ISSN 0862-8408
    Institutional research plan: CEZ:AV0Z5011922
    Keywords : patch clamp technique * electrical parameters of the cell membrane * memebrane capacity
    Subject RIV: BO - Biophysics
    Impact factor: 0.984, year: 2002

    The electrical parameters of the cell membrane are mostly estimated employing ac methods. The measurement is based on the analysis of the current(s) flowing through an access resistance and the membrane. A current/potential transducer is used at the input of the device. The parameters of this transducer, especially its feedback capacity, degrades the accuracy of the measurement and hence diminishes the suppression of mutual influences of the individual parameters. The paper suggest a possible software correction and is supplemented by remarks for practical application.
    Permanent Link: http://hdl.handle.net/11104/0040015