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Cryopreserved PBMCs can be used for the analysis of mitochondrial respiration and serve as a diagnostic tool for mitochondrial diseases

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    0605156 - FGÚ 2026 RIV NL eng J - Journal Article
    Korandová, Zuzana - Pecina, Petr - Pecinová, Alena - Koňaříková, Eliška - Tesařová, M. - Houštěk, Josef - Hansíková, H. - Ptáčková, H. - Zeman, J. - Honzík, T. - Mráček, Tomáš
    Cryopreserved PBMCs can be used for the analysis of mitochondrial respiration and serve as a diagnostic tool for mitochondrial diseases.
    Analytical Biochemistry. Roč. 698, March (2025), č. článku 115745. ISSN 0003-2697. E-ISSN 1096-0309
    R&D Projects: GA ČR(CZ) GA20-25768S; GA MZd(CZ) NU22-01-00499; GA MŠMT(CZ) LX22NPO5104
    Institutional support: RVO:67985823
    Keywords : respirometry * mitochondrial diseases * cryopreservation * OXPHOS * oxidative phosphorylation * peripheral blood mononuclear cells * PBMC * glycolysis * diagnostics
    OECD category: Biochemistry and molecular biology
    Impact factor: 2.6, year: 2023 ; AIS: 0.523, rok: 2023
    Method of publishing: Open access
    Result website:
    https://doi.org/10.1016/j.ab.2024.115745DOI: https://doi.org/10.1016/j.ab.2024.115745
    Permanent Link: https://hdl.handle.net/11104/0363485
     
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    25_0003_0605156.pdf05.8 MBPublisher’s postprintopen-access
     
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