Number of the records: 1
Enhanced SERS performance of gold nanoparticle assemblies on a cysteine-mutant Tobacco mosaic virus scaffold
- 1.
SYSNO ASEP 0602634 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Enhanced SERS performance of gold nanoparticle assemblies on a cysteine-mutant Tobacco mosaic virus scaffold Author(s) Khan, H. N. (FR)
Ortiz-Pena, N. (FR)
Da Silva, C. M. (FR)
Lau-Truong, S. (FR)
Wang, G. (US)
Dušek, Jakub (UEB-Q) ORCID, RID
Boubekeur-Lecaque, L. (FR)
Moravec, Tomáš (UEB-Q) RID, ORCID
Alloyeau, D. (FR)
Ha Duong, N. (FR)Number of authors 10 Article number 100775 Source Title Journal of Science: Advanced Materials and Devices - ISSN 2468-2284
Roč. 9, č. 4 (2024)Number of pages 9 s. Language eng - English Country VN - Viet Nam Keywords viral nanoparticles ; fabrication ; nanoscale ; chemistry ; nanorods ; delivery ; protein ; dimers ; size ; Plant virus ; Plasmonic ; In situ TEM ; Self-assembly ; Mineralization OECD category Virology R&D Projects 8J24FR014 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) TM04000026 GA TA ČR - Technology Agency of the Czech Republic (TA ČR) Method of publishing Open access Institutional support UEB-Q - RVO:61389030 UT WOS 001302197000001 EID SCOPUS 85201888877 DOI https://doi.org/10.1016/j.jsamd.2024.100775 Annotation The employment of biomolecular templates for the synthesizing nanohybrid constructs is expanding, driven by their prospective uses in biosensing and biomedical fields. Gold nanoparticles (AuNPs) and, in particular, their assemblies are especially preferred for Surface Enhanced Raman Spectroscopy (SERS) because of their ability to amplify Raman signals through localized surface plasmon resonances, thus enabling the detection of molecules at exceedingly low concentrations. Our investigative approach is dedicated to studing the role of cysteine mutants in the nucleation and assembly of AuNPs on Tobacco mosaic virus (TMV-C, carrying T158C mutation) scaffolds. Employing biomineralization and direct grafting methods, we synthesized these nanohybrids and examined them using conventional transmission electron microscopy (TEM), in situ liquid TEM, and fluorescence spectroscopy. We demonstrated that the syntheses obtained with TMV-C give denser plasmonic nanostructures, with is ideal for SERS applications. The SERS performances of these novel nanohybrids with various AuNPs sizes and densities were evaluated, revealing excellent enhancement factors for the nanosystems obtained by direct grafting that highlight their potential for the detection of biomolecules in solution. Workplace Institute of Experimental Botany Contact David Klier, knihovna@ueb.cas.cz, Tel.: 220 390 469 Year of Publishing 2025 Electronic address https://doi.org/10.1016/j.jsamd.2024.100775
Number of the records: 1