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Poly‑β‑hydroxybutyrate production by Synechocystis MT_a24 in a raceway pond using urban wastewater

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    SYSNO ASEP0584992
    Document TypeJ - Journal Article
    R&D Document TypeJournal Article
    Subsidiary JČlánek ve WOS
    TitlePoly‑β‑hydroxybutyrate production by Synechocystis MT_a24 in a raceway pond using urban wastewater
    Author(s) Grivalský, Tomáš (MBU-M) ORCID
    Lakatos, Gergely Erno (MBU-M) ORCID
    Štěrbová, Karolína (MBU-M)
    Manoel, Joao Camara (MBU-M) ORCID
    Beloša, Romana (MBU-M)
    Divoká, Petra (MBU-M) ORCID
    Kopp, J. (AT)
    Kriechbaum, R. (AT)
    Spadiut, O. (AT)
    Zwirzitz, A. (AT)
    Trenzinger, K. (AT)
    Masojídek, Jiří (MBU-M) RID, ORCID
    Article number44
    Source TitleApplied Microbiology and Biotechnology. - : Springer - ISSN 0175-7598
    Roč. 108, č. 1 (2024)
    Number of pages12 s.
    Languageeng - English
    CountryDE - Germany
    Keywordsnostoc-muscorum agardh ; carbon-dioxide ; chlorophyll-a ; cyanobacterium ; growth ; accumulation ; carotenoids ; cells ; ph ; Biodegradable plastics ; Polyhydroxybutyrate ; Synechocystis ; Urban wastewater ; Raceway pond cultivation
    OECD categoryMicrobiology
    Method of publishingLimited access
    Institutional supportMBU-M - RVO:61388971
    UT WOS001136853300001
    EID SCOPUS85181399207
    DOI https://doi.org/10.1007/s00253-023-12924-3
    AnnotationPoly-beta-hydroxybutyrate (PHB) is a potential source of biodegradable plastics that are environmentally friendly due to their complete degradation to water and carbon dioxide. This study aimed to investigate PHB production in the cyanobacterium Synechocystis sp. PCC6714 MT_a24 in an outdoor bioreactor using urban wastewater as a sole nutrient source. The culture was grown in a thin-layer raceway pond with a working volume of 100 L, reaching a biomass density of up to 3.5 g L-1 of cell dry weight (CDW). The maximum PHB content was found under nutrient-limiting conditions in the late stationary phase, reaching 23.7 +/- 2.2% PHB per CDW. These data are one of the highest reported for photosynthetic production of PHB by cyanobacteria, moreover using urban wastewater in pilot-scale cultivation which multiplies the potential of sustainable cultivation approaches. Contamination by grazers (Poterioochromonas malhamensis) was managed by culturing Synechocystis in a highly alkaline environment (pH about 10.5) which did not significantly affect the culture growth. Furthermore, the strain MT_a24 showed significant wastewater nutrient remediation removing about 72% of nitrogen and 67% of phosphorus. These trials demonstrate that the photosynthetic production of PHB by Synechocystis sp. PCC6714 MT_a24 in the outdoor thin-layer bioreactor using urban wastewater and ambient carbon dioxide. It shows a promising approach for the cost-effective and sustainable production of biodegradable carbon-negative plastics.
    WorkplaceInstitute of Microbiology
    ContactEliška Spurná, eliska.spurna@biomed.cas.cz, Tel.: 241 062 231
    Year of Publishing2025
    Electronic addresshttps://link.springer.com/article/10.1007/s00253-023-12924-3
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