Number of the records: 1
Trypanosoma brucei, a master of metabolic disguise
- 1.
SYSNO ASEP 0576571 Document Type A - Abstract R&D Document Type O - Ostatní Title Trypanosoma brucei, a master of metabolic disguise Author(s) Doleželová, Eva (BC-A) RID, ORCID
Kunzová, Michaela (BC-A) ORCID
Panicucci, Brian (BC-A)
Zíková, Alena (BC-A) RID, ORCIDNumber of authors 4 Article number 57ASM - 24 Source Title European Journal of Clinical Investigation. - : Wiley - ISSN 0014-2972
Roč. 53, č. 1 (2023)Number of pages 1 s. Publication form Online - E Action 57TH ANNUAL SCIENTIFIC MEETING-7-9 June 2023, Prague, Czech Republic Event date 07.06.2023 - 09.06.2023 VEvent location Praha Country CZ - Czech Republic Event type CST Language eng - English Country US - United States Keywords Dysregulation ; mitochondrial ; Trypanosoma brucei Subject RIV EE - Microbiology, Virology OECD category Microbiology Institutional support BC-A - RVO:60077344 UT WOS 001043106300050 Annotation Background: In the last decade, the importance of mitochondrially derived reactive oxygen species (OS) as signals in intracellular communication has been sealed. These though-to-be harmful molecules influence cellular faith decisions and can drive cells towards proliferation, apoptosis or differentiation. The OS are mainly generated as by-products during the process of oxidative phosphorylation (OXPHOS), which is completed by FoF1-ATP synthase with the formation of ATP. In trypanosomes, unicellular parasites undergoing programmed life cycle development, the cellular differentiation is linked to increased mitochondrial metabolic activity and OS production. Workplace Biology Centre (since 2006) Contact Dana Hypšová, eje@eje.cz, Tel.: 387 775 214 Year of Publishing 2024 Electronic address https://onlinelibrary.wiley.com/doi/10.1111/eci.13992
Number of the records: 1