Number of the records: 1  

Discovery of a Druggable, Cryptic Pocket in SARS-CoV-2 nsp16 Using Allosteric Inhibitors

  1. 1.
    SYSNO0576137
    TitleDiscovery of a Druggable, Cryptic Pocket in SARS-CoV-2 nsp16 Using Allosteric Inhibitors
    Author(s) Inniss, N. L. (US)
    Kozic, Ján (UOCHB-X) [350/35] ORCID
    Li, F. (CA)
    Rosas-Lemus, M. (US)
    Minasov, G. (US)
    Rybáček, Jiří (UOCHB-X) [730/73] RID, ORCID
    Zhu, Y. (CN)
    Pohl, Radek (UOCHB-X) [910/91] RID, ORCID
    Shuvalova, L. (AE)
    Rulíšek, Lubomír (UOCHB-X) [640/64] RID, ORCID
    Brunzelle, J. S. (US)
    Bednárová, Lucie (UOCHB-X) [995/99] RID, ORCID
    Štefek, Milan (UOCHB-X) [350/35]
    Kormaník, Ján Michael (UOCHB-X) [640/64]
    Andris, Erik (UOCHB-X) [640/64] ORCID
    Šebestík, Jaroslav (UOCHB-X) [810/81] RID, ORCID
    Li, A. S. M. (CA)
    Brown, P. J. (CA)
    Schmitz, U. (AE)
    Saikatendu, K. (US)
    Chang, E. (US)
    Nencka, Radim (UOCHB-X) [350/35] RID, ORCID
    Vedadi, M. (CA)
    Satchell, K. J. F. (US)
    Corespondence/seniorChang, E. - Korespondující autor
    Nencka, Radim - Korespondující autor
    Vedadi, M. - Korespondující autor
    Satchell, K. J. F. - Korespondující autor
    Source Title ACS Infectious Diseases. Roč. 9, č. 10 (2023), s. 1918-1931. - : American Chemical Society
    Document TypeČlánek v odborném periodiku
    Grant EF16_019/0000729 GA MŠMT - Ministry of Education, Youth and Sports (MEYS), CZ - Czech Republic
    NU20-05-00472 GA MZd - Ministry of Health (MZ), CZ - Czech Republic
    Institutional supportUOCHB-X - RVO:61388963
    Languageeng
    CountryUS
    Keywords coronavirus * NSP16 methyltransferase * covalent inhibitors * structural biology * antiviral
    Other sourceshttps://doi.org/10.2210/pdb8F4Y/pdb
    https://doi.org/10.2210/pdb8F4S/pdb
    URLhttps://doi.org/10.1021/acsinfecdis.3c00203
    Permanent Linkhttps://hdl.handle.net/11104/0345731
     
Number of the records: 1  

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