Combination of plant phenolics and isoquinolinium alkaloids protects gingival fibroblast and improves post-extraction healing after lower third molar extraction

0575311 - MBÚ 2024 RIV CZ eng J - Journal Article
Chytilová, K. - Galandaková, A. - Valentová, Kateřina - Tvrdý, P.
Combination of plant phenolics and isoquinolinium alkaloids protects gingival fibroblast and improves post-extraction healing after lower third molar extraction.
Biomedical Papers. Roč. 167, č. 2 (2023), s. 131-138. ISSN 1213-8118. E-ISSN 1804-7521
Institutional support: RVO:61388971
Keywords : Lonicera caerulea * Macleaya cordata * anthocyanins * isoquinolinium alkaloids * gingival fibroblast * third molar surgery
OECD category: Dentistry, oral surgery and medicine
Impact factor: 0.9, year: 2022
Method of publishing: Open access
https://biomed.papers.upol.cz/artkey/bio-202302-0005_combination-of-plant-phenolics-and-isoquinolinium-alkaloids-protects-gingival-fibroblast-and-improves-post-extr.php

Aims. The effect of polyphenolic fraction of Lonicera caerulea (PFLC) and alkaloid fraction of Macleaya cordata (AFMC) mix on the production of inflammatory mediators in human gingival fibroblasts pretreated with lipopolysaccharide (LPS) was investigated. In addition, protective effects of mucoadhesive paste containing combination of PFLC and AFMC (0.05% and 0.01%, respectively, n=15, Group A) and placebo (n=15, Group B) were evaluated in patients after surgical extraction of lower third molars.
Permanent Link: https://hdl.handle.net/11104/0345095