NMR-based Metabolomic Analysis of Endo- and Exometabolome Adaptations throught Osteogenic Differentiation of Adipose- Derived Mesenchymals Stem Cell

0574716 - ÚCHP 2024 RIV US eng C - Conference Paper (international conference)
Bispo, D.S.C. - Jesus, C.S.H. - Correia, M. - Michálková, Lenka - Oliveira, M.B. - Mano, J.F. - Gil, A.M.
NMR-based Metabolomic Analysis of Endo- and Exometabolome Adaptations throught Osteogenic Differentiation of Adipose- Derived Mesenchymals Stem Cell.
Tissue Engineering Part A, 29 (11-12). Ner Rochelle: MARY ANN LIEBERT, 2023, s. 519-520. ISSN 1937-3341. E-ISSN 1937-335X.
[Tissue Engineering and Regenerative Medicine International Society (TERMIS). Krakow (PL), 28.06.2022-01.07.2022]
Grant - others:FCT(PT) PTDC/BTM-ORG/28835/2017; FEDER(XE) POCI-01-0145-FEDER-028835; FCT(PT) UIDB/50011/2020; FCT(PT) UIDP/50011/2020
Institutional support: RVO:67985858
Keywords : mesenchymal stem cells * differentiation * osteogenesis * NMR metabolomics
OECD category: Analytical chemistry

This work has shown the great potential of NMR metabolomics to characterize the dynamic metabolism of MSC osteogenenic differentiation, ultimately enabling the potential discovery of universal biomarkers of osteogenic differentiation efficacy, with potential translation to in vivo clinical practice.
Permanent Link: https://hdl.handle.net/11104/0344828