Autonomous dried blood spot analysis by capillary electrophoresis

0573938 - ÚIACH 2024 ES eng A - Abstract
Kubáň, Pavel - Dvořák, Miloš - Ryšavá, Lenka - Moravčík, Ondrej
Autonomous dried blood spot analysis by capillary electrophoresis.
Extech 2023 Tenerife : 25th International Symposiumon Advances in Extraction Technologies. University of La Laguna, 2023. O-10.
[International Symposiumon Advances in Extraction Technologies /25./. 18.07.2023-21.07.2023, Tenerife]
R&D Projects: GA ČR(CZ) GA23-05972S
Institutional support: RVO:68081715
Keywords : dried blood spots * capillary electrophoresis * automated analysis
OECD category: Analytical chemistry

The lecture has summarized recent developments of the autonomous DBS analyses by CE achieved in our laboratory. These aimed at self-sampling exact volumes of capillary blood, reducing the volumes of the collected blood, and using plastic vials compatible with CE autosampler for safe transport of DBSs. They also aiimed at investigating and optimizing the FS capillary dimensions and CE parameters for rapid DBS elutions, programming continuous sequences for autonomous analyses of multiple DBS samples, using two interchangeable CE cartridges, and developing CE methods with various detection modes for rapid and sensitive determination of clinically important markers in DBSs.
Permanent Link: https://hdl.handle.net/11104/0344323