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Plant Extracellular Vesicles and Their Potential in Human Health Research, the Practical Approach
- 1.0562136 - ÚEB 2023 RIV CZ eng J - Journal Article
Kocholatá, M. - Malý, J. - Martinec, Jan - Auer Malinská, H.
Plant Extracellular Vesicles and Their Potential in Human Health Research, the Practical Approach.
Physiological Research. Roč. 71, č. 3 (2022), s. 327-339. ISSN 0862-8408. E-ISSN 1802-9973
R&D Projects: GA ČR(CZ) GA20-21421S
Institutional support: RVO:61389030
Keywords : Anticancer therapy * Drug delivery * Exosomes * Plant exosome-like nanovesicles * Plant extracellular vesicles
OECD category: Biophysics
Impact factor: 2.1, year: 2022
Method of publishing: Open access
https://doi.org/10.33549/physiolres.934886
Extracellular vesicles are small membrane particles (30-1000 nm) released by Bacteria, Eukaryotes and Archaea. They have been shown to play an important role in intracellular and intercellular communication, within and between kingdoms via transport of bioactive molecules. Thus, they can be involved in altering gene expression and regulation of physiological and pathological processes of the recipient. Their unique properties make extracellular vesicles a perfect candidate vector for targeted drug delivery or a biomarker. For a long time, animal and mainly mammal extracellular vesicles have been used in research. But for plants, there had been speculations about the existence of nanovesicles due to the presence of a cell wall. Today, awareness of plant extracellular vesicles is on the rise and their research has proved they have various functions, such as protein secretion, transport of bioactive molecules or defense against pathogens. Further potential of plant extracellular vesicles is stressed in this review.
Permanent Link: https://hdl.handle.net/11104/0334548
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