Activation of the integrated stress response confers vulnerability to mitoribosome-targeting antibiotics in melanoma

Vendramin, R.; Katopodi, V.; Cinque, S.; Konnova, A.; Knezevic, Z.; Adnane, S.; Verheyden, Y.; Karras, P.; Demesmaeker, E.; Bosisio, F.; Kučera, Lukáš; Rozman, Jan; Gladwyn-Ng, I.; Rizzotto, L.; Dassi, E.; Millevoi, S.; Bechter, O.; Marine, J.; Leucci, E.

doi:https://dx.doi.org/10.1084/jem.20210571

Number of the records: 1

Activation of the integrated stress response confers vulnerability to mitoribosome-targeting antibiotics in melanoma

1.

SYSNO	0555718
Title	Activation of the integrated stress response confers vulnerability to mitoribosome-targeting antibiotics in melanoma
Author(s)	Vendramin, R. (BE) Katopodi, V. (BE) Cinque, S. (BE) Konnova, A. (BE) Knezevic, Z. (BE) Adnane, S. (BE) Verheyden, Y. (BE) Karras, P. (BE) Demesmaeker, E. (BE) Bosisio, F. (BE) Kučera, Lukáš (UMG-J) [18] Rozman, Jan (UMG-J) [18] Gladwyn-Ng, I. (DE) Rizzotto, L. (BE) Dassi, E. (IT) Millevoi, S. (FR) Bechter, O. (BE) Marine, J. (BE) Leucci, E. (BE)
Corespondence/senior	Leucci, E. - Korespondující autor
Source Title	Journal of Experimental Medicine. Roč. 218, č. 9 (2021). - : Rockefeller University Press
Article number	e20210571
Document Type	Článek v odborném periodiku
Grant	LM2018126 GA MŠMT - Ministry of Education, Youth and Sports (MEYS), CZ - Czech Republic
	EF16_013/0001789 GA MŠMT - Ministry of Education, Youth and Sports (MEYS)
Institutional support	UMG-J - RVO:68378050
Language	eng
Country	US
Keywords	mitochondrial translation * drug-tolerant * cancer * resistance * metabolism * atf4 * dysfunction * doxycycline * transition * microbiome
Cooperating institutions	Kathoheke Univ Leuven, Dept Oncol, Lab RNA Canc Biol, Leuven, Belgium Vlaams Inst Biotechnol, Ctr Canc Biol, Lab Mol Canc Biol, Leuven, Belgium Kathoheke Univ Leuven, Dept Oncol, Lab Mol Canc Biol, Leuven, Belgium Kathoheke Univ Leuven, Translat Cell & Tissue Res, Leuven, Belgium Tacon Biosci, Leverkusen, Germany Kathoheke Univ Leuven, Leuven Canc Inst, Trace, Leuven, Belgium Univ Trento, Dept Cellular Computat & Integrat Biol, Lab RNA Regulatory Networks, Trento, Italy Inst Natl Sante & Rech Med Joint Res Unit 1037, Canc Res Ctr Toulouse, Toulouse, France Univ Toulouse III Paul Sabatier, Toulouse, France Lab Excellence TOUCAN, Toulouse, France Univ Ziekenhuis Leuven, Leuven Canc Inst, Dept Gen Med Oncol, Leuven, Belgium
URL	https://rupress.org/jem/article/218/9/e20210571/212494/Activation-of-the-integrated-stress-response
Permanent Link	http://hdl.handle.net/11104/0330193

Number of the records: 1