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AcanR3990 qPCR: A Novel, Highly Sensitive, Bioinformatically-Informed Assay to Detect Angiostrongylus cantonensis Infections

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    0554947 - BC 2022 RIV US eng J - Journal Article
    Sears, W.J. - Qvarnstrom, Y. - Dahlstrom, E. - Snook, K. - Kaluna, L. - Baláž, Vojtěch - Fecková, Barbora - Šlapeta, J. - Modrý, David - Jarvi, S. - Nutman, T.
    AcanR3990 qPCR: A Novel, Highly Sensitive, Bioinformatically-Informed Assay to Detect Angiostrongylus cantonensis Infections.
    Clinical Infectious Diseases. Roč. 73, č. 7 (2021), E1594-E1600. ISSN 1058-4838. E-ISSN 1537-6591
    Institutional support: RVO:60077344
    Keywords : eosinophilic meningitis * meningoencephalitis * outbreak * children * pcr * Angiostrongylus * eosinophilia * meningitis
    OECD category: Immunology
    Impact factor: 20.999, year: 2021
    Method of publishing: Open access
    https://academic.oup.com/cid/article-abstract/73/7/e1594/6012380?redirectedFrom=fulltext&login=false

    Background Angiostrongylus cantonensis (Ac), or the rat lungworm, is a major cause of eosinophilic meningitis. Humans are infected by ingesting the 3rd stage larvae from primary hosts, snails, and slugs, or paratenic hosts. The currently used molecular test is a qPCR assay targeting the ITS1 rDNA region (ITS1) of Ac.
    Permanent Link: http://hdl.handle.net/11104/0329624

     
     
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