Pathology of Angiostrongylus cantonensis infection in two model avian hosts

0553175 - BC 2022 RIV GB eng J - Journal Article
Feckova, B. - Djoehana, P. - Putnová, B. - Valastanova, M. - Petrikova, M. - Knotek, Z. - Modrý, David
Pathology of Angiostrongylus cantonensis infection in two model avian hosts.
Parasitology. Roč. 148, č. 2 (2021), s. 174-177. ISSN 0031-1820. E-ISSN 1469-8161
Institutional support: RVO:60077344
Keywords : canine neural angiostrongylosis * tawny frogmouths * neuroangiostrongyliasis * mollusks * Angiostrongylus * cantonensis * experimental * bird * chicken * quail
OECD category: Veterinary science
Impact factor: 3.243, year: 2021
Method of publishing: Limited access
https://www.cambridge.org/core/journals/parasitology/article/abs/pathology-of-angiostrongylus-cantonensis-infection-in-two-model-avian-hosts/6C0EC93076345AF8658C5AA5A56AC562

Angiostrongylus cantonensis causes severe neurological disorders in a wide range of warm-blooded animals, including several avian species. A laboratory isolate of A. cantonensis originating from French Polynesia, genotyped as clade 2, was used to assess the effect of experimental infection in chicken and Japanese quail. Low dose groups of birds were infected orally by 100 L3 larvae, high dose groups by 1500 L3 larvae and the birds in the third group were fed three infected snails, mimicking a natural infection. Clinical signs during the first week after infection, haematology, biochemistry, gross lesions and histology findings were used to assess the pathology of the infection. Some of the infected birds showed peripheral eosinophilia, while mild neurological signs were seen in others. No larvae were observed in serial sections of the central nervous system of infected birds 1 week after infection and no major gross lesions were observed during necropsy, histopathology did not reveal lesions directly attributable to A. cantonensis infection. Our results suggest that galliform birds are not highly susceptible to A. cantonensis infection and open a question of the importance of Galliformes in endemic areas as natural pest control, lowering the number of hosts carrying the infective larvae.
Permanent Link: http://hdl.handle.net/11104/0328181