Reductionist Pathways for Parasitism in Euglenozoans? Expanded Datasets Provide New Insights

0552985 - BC 2022 RIV GB eng J - Journal Article
Butenko, Anzhelika - Hammond, Michael John - Field, Mark Christian - Ginger, M. L. - Yurchenko, V. - Lukeš, Julius
Reductionist Pathways for Parasitism in Euglenozoans? Expanded Datasets Provide New Insights.
Trends in Parasitology. Roč. 37, č. 2 (2021), s. 100-116. ISSN 1471-4922. E-ISSN 1471-5007
R&D Projects: GA ČR(CZ) GA18-15962S; GA ČR(CZ) GA20-07186S; GA MŠMT(CZ) LL1601; GA MŠMT(CZ) EF16_019/0000759
Institutional support: RVO:60077344
Keywords : Euglenozoa * diplonemids * kinetoplastids
OECD category: Biochemistry and molecular biology
Impact factor: 10.528, year: 2021
Method of publishing: Limited access
https://www.sciencedirect.com/science/article/pii/S1471492220302646?via%3Dihub

The unicellular trypanosomatids belong to the phylum Euglenozoa and all known species are obligate parasites. Distinct lineages infect plants, invertebrates, and vertebrates, including humans. Genome data formarine diplonemids, together with freshwater euglenids and free-living kinetoplastids, the closest known nonparasitic relatives to trypanosomatids, recently became available. Robust phylogenetic reconstructions across Euglenozoa are now possible and place the results of parasite-focused studies into an evolutionary context. Here we discuss recent advances in identifying the factors shaping the evolution of Euglenozoa, focusing on ancestral features generally considered parasite-specific. Remarkably, most of these predate the transition(s) to parasitism, suggesting that the presence of certain preconditions makes a significant lifestyle change more likely.
Permanent Link: http://hdl.handle.net/11104/0328035