Sequence of the supernumerary B chromosome of maize provides insight into its drive mechanism and evolution

0548808 - ÚEB 2022 RIV US eng J - Journal Article
Blavet, Nicolas - Yang, H. - Su, H. Y. - Solanský, Pavel - Douglas, R. N. - Karafiátová, Miroslava - Šimková, Lucie - Zhang, J. - Liu, Y. - Hou, J. - Shi, X. - Chen, C. - El-Walid, M. - McCaw, M. E. - Albert, P. S. - Gao, Z. - Zhao, C. - Ben-Zvi, G. - Glick, L. - Kol, G. - Shi, J. - Vrána, Jan - Šimková, Hana - Lamb, J. H. - Newton, K. - Dawe, R. K. - Doležel, Jaroslav - Ji, T. - Baruch, K. - Cheng, J. - Han, F. Z. - Birchler, J. A. - Bartoš, Jan
Sequence of the supernumerary B chromosome of maize provides insight into its drive mechanism and evolution.
Proceedings of the National Academy of Sciences of the United States of America. Roč. 118, č. 23 (2021), č. článku e2104254118. ISSN 0027-8424. E-ISSN 1091-6490
R&D Projects: GA ČR(CZ) GJ18-12338Y; GA MŠMT(CZ) EF16_019/0000827
Institutional support: RVO:61389030
Keywords : B chromosome * Genetic drive * Nondisjunction * Preferential fertilization
OECD category: Cell biology
Impact factor: 12.779, year: 2021
Method of publishing: Open access
http://doi.org/10.1073/PNAS.2104254118

B chromosomes are enigmatic elements in thousands of plant and animal genomes that persist in populations despite being nonessential. They circumvent the laws of Mendelian inheritance but the molecular mechanisms underlying this behavior remain unknown. Here we present the sequence, annotation, and analysis of the maize B chromosome providing insight into its drive mechanism. The sequence assembly reveals detailed locations of the elements involved with the cis and trans functions of its drive mechanism, consisting of nondisjunction at the second pollen mitosis and preferential fertilization of the egg by the B-containing sperm. We identified 758 protein-coding genes in 125.9 Mb of B chromosome sequence, of which at least 88 are expressed. Our results demonstrate that transposable elements in the B chromosome are shared with the standard A chromosome set but multiple lines of evidence fail to detect a syntenic genic region in the A chromosomes, suggesting a distant origin. The current gene content is a result of continuous transfer from the A chromosomal complement over an extended evolutionary time with subsequent degradation but with selection for maintenance of this nonvital chromosome.
Permanent Link: http://hdl.handle.net/11104/0324856