Magneto-immunoassay of cancer biomarkers: Recent progress and challenges in biomedical analysis

0543931 - ÚJF 2022 RIV NL eng J - Journal Article
Kavetskyy, T. - Alipour, M. - Smutok, O. - Mushynska, O. - Kiv, A. - Fink, Dietmar - Farshchi, F. - Ahmadian, E. - Hasanzadeh, M.
Magneto-immunoassay of cancer biomarkers: Recent progress and challenges in biomedical analysis.
Microchemical Journal. Roč. 167, AUG (2021), č. článku 106320. ISSN 0026-265X. E-ISSN 1095-9149
Institutional support: RVO:61389005
Keywords : cancer * nanobiomedicine * biomedical analysis * biotechnology * magnetic nanomaterials
OECD category: Analytical chemistry
Impact factor: 5.304, year: 2021
Method of publishing: Limited access
https://doi.org/10.1016/j.microc.2021.106320

Ultrasensitive biomarker sensing has been used to develop novel strategies in detecting early stage cancer. Due to their unique characteristics, ie, ease of synthesis, conductivity and bio-compatibility, iron magnetic nanoparticles (MNPs) are exceptional nanomaterial in theragnostics. The current review focuses the critical role of iron MNPs in the development of several immunoassay technologies including electrochemical, electrochemiluminescent, photoelectrochemical, optical and microfluidic biosensors. Type and composition of magnetic particles, detection methods, relative specificity and sensitivity is discussed. Advantages and limitations of various strategies for label-free immunosensing of cancer biomarkers are explored.
Permanent Link: http://hdl.handle.net/11104/0321025