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Imidazo[1,2-c]pyrimidin-5(6H)-one inhibitors of CDK2: Synthesis, kinase inhibition and co-crystal structure

  1. 1.
    SYSNO0541414
    TitleImidazo[1,2-c]pyrimidin-5(6H)-one inhibitors of CDK2: Synthesis, kinase inhibition and co-crystal structure
    Author(s) Jansa, J. (CZ)
    Jorda, R. (CZ)
    Škerlová, Jana (UOCHB-X) [930/93] ORCID
    Pachl, Petr (UOCHB-X) [930/93] RID, ORCID
    Peřina, M. (CZ)
    Řezníčková, E. (CZ)
    Heger, T. (CZ)
    Gucký, T. (CZ)
    Řezáčová, Pavlína (UOCHB-X) [930/93] RID, ORCID
    Lyčka, A. (CZ)
    Kryštof, V. (CZ)
    Corespondence/seniorKryštof, V. - Korespondující autor
    Source Title European Journal of Medicinal Chemistry. Roč. 216, Apr 15 (2021). - : Elsevier
    Article number113309
    Document TypeČlánek v odborném periodiku
    Grant EF16_019/0000729 GA MŠMT - Ministry of Education, Youth and Sports (MEYS), CZ - Czech Republic
    Institutional supportUOCHB-X - RVO:61388963
    Languageeng
    CountryFR
    Keywords activity assay * Co-crystal * cyclin-dependent kinase 2 * imidazo[1,2-c]pyrimidin-5(6H)-one * ITC * kinase inhibitor * X-ray crystallography
    Cooperating institutions Univerzita Palackého v Olomouci
    Výzkumný ústav organických syntéz Rybitví (Czech Republic)
    Univerzita Karlova v Praze (Czech Republic)
    URLhttps://doi.org/10.1016/j.ejmech.2021.113309
    Permanent Linkhttp://hdl.handle.net/11104/0318978
     
Number of the records: 1  

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