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Megahertz single-particle imaging at the European XFEL

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    0537252 - FZÚ 2021 RIV DE eng J - Journal Article
    Sobolev, E. - Zolotarev, S. - Giewekemeyer, K. - Andreasson, Jakob - Kulyk, Olena … Total 65 authors
    Megahertz single-particle imaging at the European XFEL.
    COMMUNICATIONS PHYSICS. Roč. 3, č. 1 (2020), s. 1-11, č. článku 97. ISSN 2399-3650. E-ISSN 2399-3650
    R&D Projects: GA MŠMT EF16_019/0000789
    Grant - others:OP VVV - ADONIS(XE) CZ.02.1.01/0.0/0.0/16_019/0000789
    Institutional support: RVO:68378271
    Keywords : X-ray laser * Free Electron Lasers * femtosecond
    OECD category: Atomic, molecular and chemical physics (physics of atoms and molecules including collision, interaction with radiation, magnetic resonances, Mössbauer effect)
    Impact factor: 6.368, year: 2020
    Method of publishing: Open access

    The emergence of high repetition-rate X-ray free-electron lasers (XFELs) powered by superconducting accelerator technology enables the measurement of significantly more experimental data per day than was previously possible. The European XFEL is expected to provide 27,000 pulses per second, over two orders of magnitude more than any other XFEL. The increased pulse rate is a key enabling factor for single-particle X-ray diffractive imaging, which relies on averaging the weak diffraction signal from single biological particles. Taking full advantage of this new capability requires that all experimental steps, from sample preparation and delivery to the acquisition of diffraction patterns, are compatible with the increased pulse repetition rate. Here, we show that single-particle imaging can be performed using X-ray pulses at megahertz repetition rates.
    Permanent Link: http://hdl.handle.net/11104/0314988

     
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