Effect of static magnetic field on DNA synthesis: the interplay between DNA chirality and magnetic field left‐right asymmetry

0533093 - FZÚ 2021 RIV US eng J - Journal Article
Yang, X. - Li, Z. - Polyakova, Tetyana - Dejneka, Alexandr - Zablotskyy, Vitaliy A. - Zhang, X.
Effect of static magnetic field on DNA synthesis: the interplay between DNA chirality and magnetic field left‐right asymmetry.
FASEB BioAdvances. Roč. 2, č. 4 (2020), s. 254-263. ISSN 2573-9832
R&D Projects: GA MŠMT(CZ) EF16_019/0000760
Grant - others:OP VVV - SOLID21(XE) CZ.02.1.01/0.0/0.0/16_019/0000760
Institutional support: RVO:68378271
Keywords : biomagnetic effects * DNA synthesis * homochirality * left-right asymmetry * magnetic field
OECD category: Condensed matter physics (including formerly solid state physics, supercond.)
Method of publishing: Open access

Interactions between magnetic fields (MFs) and living cells may stimulate a large variety of cellular responses to a MF, while the underlying intracellular mechanisms still remain a great puzzle. On a fundamental level, the MF — cell interaction is affected by the two broken symmetries: (a) left‐right (LR) asymmetry of the MF and (b) chirality of DNA molecules carrying electric charges and subjected to the Lorentz force when moving in a MF. Here we report on the chirality‐driven effect of static magnetic fields (SMFs) on DNA synthesis. This newly discovered effect reveals how the interplay between two fundamental features of symmetry in living and inanimate nature—DNA chirality and the inherent features of MFs to distinguish the left and right—manifests itself in different DNA synthesis rates in the upward and downward SMFs, consequently resulting in unequal cell proliferation for the two directions of the field.
Permanent Link: http://hdl.handle.net/11104/0311581