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Advances in Disease Models

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    0523221 - ÚMG 2020 RIV CZ eng M - Monography Chapter
    Šťastná, Monika - Janečková, Lucie - Kořínek, Vladimír
    Mouse xenograft models of human colorectal cancer.
    Advances in Disease Models. Praha: OPTIO CZ, 2019 - (Bartůněk, P.), s. 71-81. ISBN 978-80-88011-06-4
    R&D Projects: GA MŠMT LO1419
    Institutional support: RVO:68378050
    Keywords : mouse xenograft model * human colorectal cancer * tumor organoids
    OECD category: Cell biology

    In this chapter, we discuss xenotransplantations used to study the properties of human colorectal cancer. The text provides an overview of available immunodeficient mouse strains, sample application methods, and the most common sites for application of colorectal tumor samples. In addition, the advantages and disadvantages of administration using standardized cell lines, tumor organoids, or fresh patient samples are described.

    Permanent Link: http://hdl.handle.net/11104/0307598

     
     
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