0510301 - ÚEB 2020 RIV GB eng J - Journal Article
Kadlecová, Alena - Maková, Barbara - Artal-Sanz, M. - Strnad, Miroslav - Voller, Jiří
The plant hormone kinetin in disease therapy and healthy aging.
Ageing Research Reviews. Roč. 55, NOV (2019), č. článku 100958. ISSN 1568-1637. E-ISSN 1872-9649
Institutional support: RVO:61389030
Keywords : Age-related diseases * Aging * Cytokinin * Kinetin
OECD category: Pharmacology and pharmacy
Impact factor: 10.616, year: 2019
Method of publishing: Open access
http://dx.doi.org/10.1016/j.arr.2019.100958

It has been more than 60 years since the discovery of kinetin, the first known member of a group of plant hormones called cytokinins. In this review we summarize the health-promoting activity of kinetin in animal systems, ranging from cells cultured in vitro through invertebrates to mammals. Kinetin has been shown to modulate aging, to delay age-related physiological decline and to protect against some neurodegenerative diseases. We also review studies on its mechanism of action, as well as point out gaps in our current knowledge.
Permanent Link: http://hdl.handle.net/11104/0300813