Number of the records: 1
Temporal Ordering in Endocytic Clathrin-Coated Vesicle Formation via AP2 Phosphorylation
- 1.0507757 - ÚTIA 2020 RIV US eng J - Journal Article
Wrobel, A.G. - Kadlecova, Z. - Kamenický, Jan - Yang, J.C. - Herrmann, T. - Kelly, B.T. - McCoy, A.J. - Evans, P.R. - Martin, S. - Muller, S. - Šroubek, Filip - Neuhaus, D. - Honing, S. - Owen, D.J.
Temporal Ordering in Endocytic Clathrin-Coated Vesicle Formation via AP2 Phosphorylation.
Developmental Cell. Roč. 50, č. 4 (2019), s. 494-508, č. článku e11. ISSN 1534-5807. E-ISSN 1878-1551
R&D Projects: GA ČR GA18-05360S
Institutional support: RVO:67985556
Keywords : clathrin-coated pit * NECAP protein
OECD category: Computer hardware and architecture
Impact factor: 10.092, year: 2019
Method of publishing: Open access
http://library.utia.cas.cz/separaty/2019/ZOI/sroubek-0507757.pdf https://www.sciencedirect.com/science/article/pii/S1534580719306239
Wrobel et al. show that phosphorylation of the mammalian endocytic AP2 adaptor causes a conformational change that allows it to efficiently bind the protein NECAP. This, in turn, recruits membrane-remodeling proteins into clathrin-coated pits, which drive their formation toward final scission from the parent membrane.
Permanent Link: http://hdl.handle.net/11104/0298745
Number of the records: 1