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Study of Synthetic Oligonacleotides Containing Guanine by Voltammetry on a Graphite Electrode
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SYSNO ASEP 0506554 Document Type C - Proceedings Paper (int. conf.) R&D Document Type Conference Paper Title Study of Synthetic Oligonacleotides Containing Guanine by Voltammetry on a Graphite Electrode Author(s) Hejduková, M. (CZ)
Špaček, Jan (BFU-R) ORCID
Fojta, Miroslav (BFU-R) RID, ORCID
Havran, L. (CZ)
Renciuk, D. (CZ)Number of authors 5 Source Title XXXVIII. Moderní elektrochemické metody. Sborník přednášek. - Ústí nad Labem : Best Servis, 2018 / Navrátil T. ; Fojta M. ; Schwarzová K. - ISBN 978-80-905221-6-9 Pages č. 2018 (2018), s. 74-76 Number of pages 3 s. Publication form Print - P Action Moderní elektrochemické metody /38./ Event date 21.05.2018 - 25.05.2018 VEvent location Jetřichovice Country CZ - Czech Republic Event type WRD Language eng - English Country CZ - Czech Republic Keywords Oligonucleotides ; Pyrolytic graphite electrode ; Linear sweep voltammetry Subject RIV CF - Physical ; Theoretical Chemistry OECD category Physical chemistry R&D Projects GA16-01625S GA ČR - Czech Science Foundation (CSF) EF15_003/0000477 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) Institutional support BFU-R - RVO:68081707 UT WOS 000464596500017 Annotation Electrochemical oxidation of specifically designed DNA hexamers containing guanine has been studied in aqueous acetate buffet (pH 5) at a pyrolytic graphite electrode (PGE) by linear sweep voltammetry (LSV) Influence of the oligonucleotide composition and concentration was investigated It seems that short oligonucleotides containing guanine produce oxidation signals. which are sensitive to their structural properties Simple electrochemical techniques us may be useful tool for monitoring of structural changes of DNA. Workplace Institute of Biophysics Contact Jana Poláková, polakova@ibp.cz, Tel.: 541 517 244 Year of Publishing 2020
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