Tigray orthohantavirus infects two related rodent species adapted to different elevations in Ethiopia

0505874 - ÚBO 2020 RIV US eng J - Journal Article
Meheretu, Y. - Stanley, W. T. - Craig, E. W. - Goüy de Bellocq, Joëlle - Bryja, Josef - Leirs, H. - Pahlmann, M. - Günther, S.
Tigray orthohantavirus infects two related rodent species adapted to different elevations in Ethiopia.
Vector-Borne and Zoonotic Diseases. Roč. 19, č. 12 (2019), s. 950-953. ISSN 1530-3667. E-ISSN 1557-7759
R&D Projects: GA ČR(CZ) GA18-17398S
Institutional support: RVO:68081766
Keywords : orthohantavirus * Stenocephalemys * Afroalpine * phylogeny * Simien Mountains
OECD category: Zoology
Impact factor: 2.249, year: 2019
Method of publishing: Open access
http://dx.doi.org/10.1089/vbz.2019.2452

Orthohantaviruses are RNA viruses that some members are known to cause severe zoonotic diseases in humans. Orthohantaviruses are hosted by rodents, soricomorphs (shrews and moles), and bats. Only two orthohantaviruses associated with murid rodents are known in Africa, Sangassou orthohantavirus (SANGV) in two species of African wood mice (Hylomyscus), and Tigray orthohantavirus (TIGV) in the Ethiopian white-footed rat (Stenocephalemys albipes). In this article, we report evidence that, like SANGV, two strains of TIGV occur in two genetically related rodent species, S. albipes and S. sp. A, occupying different elevational zones in the same mountain. Investigating the other members of the genus Stenocephalemys for TIGV could reveal the real diversity of TIGV in the genus.
Permanent Link: http://hdl.handle.net/11104/0298297