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PRIMIN DERIVATIVES, METHOD OF PREPARATION THEREOF AND USE THEREOF
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SYSNO ASEP 0499587 Document Type P - Patent R&D Document Type Patent or other outcome protected by special legislation Title PRIMIN DERIVATIVES, METHOD OF PREPARATION THEREOF AND USE THEREOF Author(s) Landa, Přemysl (UEB-Q) RID, ORCID
Šíša, Miroslav (UEB-Q) ORCID
Vaněk, Tomáš (UEB-Q) RID, ORCID
Rárová, Lucie (UEB-Q) RID, ORCIDYear of issue 2018 Possible third party use of the result A - Pro využití výsledku jiným subjektem je vždy nutné nabytí licence Royalty requested A - Poskytovatel licence požaduje licenční poplatek Patent no. or utility model no. or industrial design no. ZA2017/08339 Date of the patent acceptance 19.12.2018 Name of the patent owner Ústav experimentální botaniky AV ČR, v. v. i. Code of the issuer name ZA001 - Companies and Intellectual Property Registration Office (CIPRO) Pretoria Current use B - Patent je využíván na základě uzavřené licenční smlouvy mezi vlastníkem a uživatelem Language eng - English Keywords primin derivatives ; Anti-inflammatory activity ; pharmaceutical industry Subject RIV CC - Organic Chemistry OECD category Organic chemistry Institutional support UEB-Q - RVO:61389030 Annotation The present invention provides primin derivatives of general formula II and/or III, wherein R1 is selected from the group consisting of methyl and hydrogen, R2 is selected from the group consisting of methoxy, hydroxy, hydrogen, R3 is selected from the group consisting of bromine atom, n-(CH2)nCH3, n-(CH2)nCH2-OH, n-(CH2)nCH2-NH2, wherein n=1 to 16, X is selected from the group consisting of: hydroxy, amino in formula II, keto, imino in formula III, Y is selected from the group consisting of hydrogen, hydroxy in formula II, keto in formula III, whereas, when X and Y are keto groups (in formula III) or hydroxy groups (in formula II), R3 is pentyl and R1 is methyl, then R2 is not hydrogen. These derivatives are suitable for use as anti-inflammatory, pain-relieving and asthma-relieving agents. Workplace Institute of Experimental Botany Contact David Klier, knihovna@ueb.cas.cz, Tel.: 220 390 469 Year of Publishing 2019 Electronic address https://patentsearch.cipc.co.za/patents/patdetails.aspx?data=oXc%2bbAUVDnkljcXGVvMYJInzt4ORl9PsUIjgtDCYTDDBQIybCiTb8aYVHmyPy5JjmE2ZpsfiByCZHGUPJFyJ4AOTK5JBmzoHRhPC31t8njkLUwHB%2bsZhkpD0ye82P4mq
Number of the records: 1