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Stable isotope compounds - production, detection, and application
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SYSNO ASEP 0491815 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title Stable isotope compounds - production, detection, and application Author(s) Zachleder, Vilém (MBU-M) ORCID
Vítová, Milada (MBU-M) RID, ORCID
Hlavová, Monika (MBU-M)
Moudříková, Š. (CZ)
Mojzeš, P. (CZ)
Heumann, H. (DE)
Becher, J.R. (DE)
Bišová, Kateřina (MBU-M) RIDSource Title Biotechnology Advances. - : Elsevier - ISSN 0734-9750
Roč. 36, 3 SI (2018), s. 784-797Number of pages 14 s. Language eng - English Country US - United States Keywords Algae ; Deuterium ; Magnesium Subject RIV EE - Microbiology, Virology OECD category Microbiology R&D Projects GA17-06264S GA ČR - Czech Science Foundation (CSF) Institutional support MBU-M - RVO:61388971 UT WOS 000432104800015 EID SCOPUS 85040595345 DOI 10.1016/j.biotechadv.2018.01.010 Annotation Stable isotopes are used in wide fields of application from natural tracers in biology, geology and archeology through studies of metabolic fluxes to their application as tracers in quantitative proteomics and structural biology. We review the use of stable isotopes of biogenic elements (H, C, N, O, S, Mg, Se) with the emphasis on hydrogen and its heavy isotope deuterium. We will discuss the limitations of enriching various compounds in stable isotopes when produced in living organisms. Finally, we overview methods for measuring stable isotopes, focusing on methods for detection in single cells in situ and their exploitation in modern biotechnologies. Workplace Institute of Microbiology Contact Eliška Spurná, eliska.spurna@biomed.cas.cz, Tel.: 241 062 231 Year of Publishing 2019
Number of the records: 1