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Discovery of N-2-(4-Amino-cyclohexyl)-9-cyclopentyl-N-6-(4-morpholin-4-ylmethyl-phenyl)-9H-purine-2,6-diamine as a Potent FLT3 Kinase Inhibitor for Acute Myeloid Leukemia with FLT3 Mutations

  1. 1.
    SYSNO0490059
    TitleDiscovery of N-2-(4-Amino-cyclohexyl)-9-cyclopentyl-N-6-(4-morpholin-4-ylmethyl-phenyl)-9H-purine-2,6-diamine as a Potent FLT3 Kinase Inhibitor for Acute Myeloid Leukemia with FLT3 Mutations
    Author(s) Gucký, T. (CZ)
    Řezníčková, Eva (UEB-Q) RID, ORCID
    Radošová Muchová, T. (CZ)
    Jorda, Radek (UEB-Q) ORCID, RID
    Klejová, Z. (CZ)
    Malínková, V. (CZ)
    Berka, K. (CZ)
    Bazgier, V. (CZ)
    Ajani, Haresh (UOCHB-X) [610/61] ORCID, RID
    Lepšík, Martin (UOCHB-X) [610/61] RID, ORCID
    Divoký, V. (CZ)
    Kryštof, Vladimír (UEB-Q) RID, ORCID
    Corespondence/seniorKryštof, Vladimír - Korespondující autor
    Source Title Journal of Medicinal Chemistry. Roč. 61, č. 9 (2018), s. 3855-3869. - : American Chemical Society
    Document TypeČlánek v odborném periodiku
    Grant LO1204 GA MŠMT - Ministry of Education, Youth and Sports (MEYS), CZ - Czech Republic
    LM2015047 GA MŠMT - Ministry of Education, Youth and Sports (MEYS), CZ - Czech Republic
    EF16_019/0000729 GA MŠMT - Ministry of Education, Youth and Sports (MEYS), CZ - Czech Republic
    Institutional supportUEB-Q - RVO:61389030 ; UOCHB-X - RVO:61388963
    Languageeng
    CountryUS
    Keywords INTERNAL TANDEM DUPLICATION * AMG 925 * QUIZARTINIB
    Permanent Linkhttp://hdl.handle.net/11104/0284356
    FileDownloadSizeCommentaryVersionAccess
    2018_Gucky_JOURNAL OF MEDICINAL CHEMISTRY_3855.pdf15.1 MBOtheropen-access
     
Number of the records: 1  

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