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The hidden function of egg white antimicrobials: egg weight-dependent effects of avidin on avian embryo survival and hatchling phenotype
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SYSNO ASEP 0489234 Document Type J - Journal Article R&D Document Type Journal Article Subsidiary J Článek ve WOS Title The hidden function of egg white antimicrobials: egg weight-dependent effects of avidin on avian embryo survival and hatchling phenotype Author(s) Krkavcová, E. (CZ)
Kreisinger, J. (CZ)
Hyánková, L. (CZ)
Hyršl, P. (CZ)
Javůrková, Veronika (UBO-W) RID, ORCID, SAINumber of authors 5 Article number bio031518 Source Title Biology Open. - : Company of Biologists - ISSN 2046-6390
Roč. 7, č. 4 (2018)Number of pages 9 s. Language eng - English Country GB - United Kingdom Keywords albumen ; maternal effects ; antimicrobials ; avidin-biotin complex ; embryogenesis ; plasma complement Subject RIV EA - Cell Biology OECD category Biology (theoretical, mathematical, thermal, cryobiology, biological rhythm), Evolutionary biology R&D Projects EE2.3.20.0303 GA MŠMT - Ministry of Education, Youth and Sports (MEYS) Institutional support UBO-W - RVO:68081766 UT WOS 000430172200005 EID SCOPUS 85045406051 DOI 10.1242/bio.031518 Annotation Avidin is a key egg white antimicrobial protein with strong binding capacity for biotin, an essential growth and immune cell precursor. As such, it is assumed to have a pronounced, though still poorly explored, effect on hatchling phenotype. We tested the effect of experimentally increased egg white avidin concentration (AVIDIN+) on hatching success, chick morphology, post-hatching growth performance and innate immune function in a model bird, Japanese quail (Coturnix japonica). Probability of embryo survival in the late embryonic phase increased with increasing eggweight in control eggs, but not in AVIDIN+ eggs. Chicks hatching from lighter AVIDIN+ eggs had a shorter tarsus than chicks hatching fromheavier AVIDIN+ eggs. This suggests that an increase in egg white avidin favours embryo survival in lighter eggs during late embryogenesis, but at the expense of reduced structural body size. Plasma complement activity in 6-day-old AVIDIN+ chicks decreased with increasing body mass and tarsus length, the opposite was observed in control chicks, implying that the later post-hatching innate immune function of larger chicks was compromised by an increase in egg white avidin concentration. Here, we document an important role of egg white antimicrobials in maintenance of embryo viability, avian hatchling morphology and immune phenotype. Workplace Institute of Vertebrate Biology Contact Hana Slabáková, slabakova@ivb.cz, Tel.: 543 422 524 Year of Publishing 2019
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